Topline Presentation Points
Overview of response adaptation trial data:
- UK RAPID study
- ‘Although the non-inferiority margin was exceeded in this study, the results suggest that radiotherapy can be avoided for patients with negative PET findings’
Radford et al NEJM (2015) 372:17; 1598-1607
- EORTC H10 study
- ‘In the F group, CMT results in better early disease control; however in the U group benefit of CMT seems to be less clinically relevant, and treatment with chemotherapy only is defensible in individual patients’
Andre et al (2017) JCO