Topline Presentation Points
Recognize indications to treat and interpret the molecular profile to inform treatment initiation.
Treatment decisions and the Canadian Perspective
- Informed by Age, Fitness and Kidney Function
- CADTH Provisional Funding Algorithm Diagram for CLL
- CADTH Reimbursement Review. Provisional Funding Algorithm for Chronic Lymphocytic Leukemia. Final Report. May 18, 2021.
- [Select] Trial data add further context (ECOG 1912, CLL14, ELEVATE-TN, ALLIANCE)
- BTKi Have Shown Favourable Efficacy Against del(17p)/TP53 Aberrations in Patients With TN CLL
- Patients with TP53 mutation or del(17p) should receive front line therapy with BTKi