Introduction
Dr. Alison Moskowitz (Memorial Sloan Kettering Cancer Centre, NY) connects virtually with CARE™ Hematology Faculty lead, Dr. Peter Anglin (Stronach Regional Cancer Centre, ON), to discuss treatment of advanced Hodgkin Lymphoma.
Case
52-year-old woman
Presents with advanced stage cHL
- Considered stage 4 advanced cHL
- ECOG performance status 0-1
Variation on Case
21 vs 52-year-old woman
Supplemental Discussion
BV-AVD – efficacy and safety
Back to case of 52-year-old
- Approach with regression of disease with small area of Deauville 4
(Refer to the notes below the video stream for timestamps that can be used to navigate video.)
Video Navigation
Case 1 [0:35 – 3:49]
52-year-old woman
Presents with advanced stage cHL
- Nodular Sclerosis (NS) sub type
Adenopathy above and below diaphragm
- Non bulky
Pulmonary nodules up to 1.7cm that also lights up on her PET scan
- In addition PET scan lights up on several areas of bone
Considered stage 4 advanced cHL
ECOG performance status 0-1
A bit of fatigue
No other major medical issues
Variation on Case [3:50 – 5:05]
- 21 vs 52-year-old woman
- Peripheral neuropathy touched on
Supplemental Discussion [5:05 – 7:39]
Data for pregnancy suggests BV-AVD no worse than ABVD
- Recommending fertility preservation?
GCSF is needed
- Approach to administration?
Back to case of 52-year-old [7:40 – 9:25]
PET2 was done. Showed regression of disease with a small area of Deauville 4 seen in one nodal group
- How do you approach?
Concluding Remarks [9:25 – 9:50]
CARE™ case discussion series is supported by Seagen Canada. [ seagen.ca ]
